Of course, if I used it all the time I would become familiar with the features and it would be second nature. I know at the University, there is lots of support and training for using Blackboard and I wonder if the same is true for Moodle and that a whole school district could adopt it for its course management system. According to their site you can, but I would worry about server connectivity, back up and help for the manager as well as the student. And even though you have to pay for Blackboard, I believe there is more support for all the users. Now mind you, this is based on limited use by my part, but I did read many reviews about both systems.
I could see how Moodle would be great for using with perhaps personal groups like a book club, a 4H group or perhaps even a athletic team. This would be a great way to post information for everyone and disseminate information in an effective way that didn't require a lot of paper, really be green and keep things digital. Of course that means that all members have to have internet access and we have to keep in mind that even though it seems everywhere, not everyone still has it at home. (I even know a few professors that are too cheap to have it at home, if you can believe that).
Overall, course management for a course needs to be determined by the school so that there is consistency and then there needs to be support for whatever system. If it is at a personal level, I could really take advantage of an open source site like Moodle and its affordability, and I do have enrollment in some personal educational sites that are really helpful.